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Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes

Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires learning the dynamics of the cancer evolutionary process. We present here a large-scale analysis of the dynamics of this evolutionary proces...

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Detalhes bibliográficos
Main Authors: Ostrow, Sheli L., Barshir, Ruth, DeGregori, James, Yeger-Lotem, Esti, Hershberg, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945297/
https://ncbi.nlm.nih.gov/pubmed/24603726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004239
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