Proteomic Identification and Quantification of S-glutathionylation in Mouse Macrophages Using Resin-Assisted Enrichment and Isobaric Labeling

S-glutathionylation (SSG) is an important regulatory posttranslational modification on protein cysteine (Cys) thiols, yet the role of specific cysteine residues as targets of modification is poorly understood. We report a novel quantitative mass spectrometry (MS)-based proteomic method for site-spec...

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Hauptverfasser: Su, Dian, Gaffrey, Matthew J., Guo, Jia, Hatchell, Kayla E., Chu, Rosalie K., Clauss, Therese R. W., Aldrich, Joshua T., Wu, Si, Purvine, Sam, Camp, David G., Smith, Richard D., Thrall, Brian D., Qian, Wei-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945121/
https://ncbi.nlm.nih.gov/pubmed/24333276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.12.004
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