Proteomic Identification and Quantification of S-glutathionylation in Mouse Macrophages Using Resin-Assisted Enrichment and Isobaric Labeling

S-glutathionylation (SSG) is an important regulatory posttranslational modification on protein cysteine (Cys) thiols, yet the role of specific cysteine residues as targets of modification is poorly understood. We report a novel quantitative mass spectrometry (MS)-based proteomic method for site-spec...

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Main Authors: Su, Dian, Gaffrey, Matthew J., Guo, Jia, Hatchell, Kayla E., Chu, Rosalie K., Clauss, Therese R. W., Aldrich, Joshua T., Wu, Si, Purvine, Sam, Camp, David G., Smith, Richard D., Thrall, Brian D., Qian, Wei-Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945121/
https://ncbi.nlm.nih.gov/pubmed/24333276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.12.004
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