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Proteomic Identification and Quantification of S-glutathionylation in Mouse Macrophages Using Resin-Assisted Enrichment and Isobaric Labeling

S-glutathionylation (SSG) is an important regulatory posttranslational modification on protein cysteine (Cys) thiols, yet the role of specific cysteine residues as targets of modification is poorly understood. We report a novel quantitative mass spectrometry (MS)-based proteomic method for site-spec...

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Detalhes bibliográficos
Main Authors: Su, Dian, Gaffrey, Matthew J., Guo, Jia, Hatchell, Kayla E., Chu, Rosalie K., Clauss, Therese R. W., Aldrich, Joshua T., Wu, Si, Purvine, Sam, Camp, David G., Smith, Richard D., Thrall, Brian D., Qian, Wei-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945121/
https://ncbi.nlm.nih.gov/pubmed/24333276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.12.004
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