Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling.

Eitemau Tebyg

• Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.
  gan: Woodcock, J M, et al.
  Cyhoeddwyd: (1994)
• Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation.
  gan: Sakamaki, K, et al.
  Cyhoeddwyd: (1992)
• Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit
  gan: Perugini, Michelle, et al.
  Cyhoeddwyd: (2010)
• Slow-Dissociation Effect of Common Signaling Subunit β on IL5 and GM-CSF Receptor Assembly
  gan: Ishino, Tetsuya, et al.
  Cyhoeddwyd: (2008)
• Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.
  gan: Dirksen, U, et al.
  Cyhoeddwyd: (1997)