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Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3.

Amplification and/or overexpression of HER2/neu and HER3 genes have been implicated in the development of cancer in humans. The fact that these receptor tyrosine kinases (RTKs) are frequently coexpressed in tumor-derived cell lines and that heterodimers form high affinity binding sites for heregulin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Wallasch, C, Weiss, F U, Niederfellner, G, Jallal, B, Issing, W, Ullrich, A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00101.x
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