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Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

Granzyme A, a granule-associated serine proteinase of activated cytotoxic T cells and natural killer cells, has been reported to play a critical role in DNA fragmentation of target cells. To address the question of the biological role of granzyme A, we have now generated a granzyme A-deficient mouse...

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Main Authors: Ebnet, K, Hausmann, M, Lehmann-Grube, F, Müllbacher, A, Kopf, M, Lamers, M, Simon, M M
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC394506/
https://ncbi.nlm.nih.gov/pubmed/7556064
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