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Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats

Diabetes detrimentally affects the musculoskeletal system by stiffening the collagen matrix due to increased advanced glycation end products (AGEs). In this study, tibiae and tendon from Zucker diabetic Sprague-Dawley (ZDSD) rats were compared to Sprague-Dawley derived controls (CD) using Atomic For...

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Bibliografiska uppgifter
Huvudupphovsmän: Hammond, Max A, Gallant, Maxime A, Burr, David B, Wallace, Joseph M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944921/
https://ncbi.nlm.nih.gov/pubmed/24269519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.11.015
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