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In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs.

An in vitro reconstitution/splicing complementation system has been developed which has allowed the investigation of the role of mammalian U2 and U5 snRNP components in splicing. U2 or U5 snRNP cores are first reconstituted from purified native snRNP core proteins and snRNA in the absence of cellula...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Ségault, V, Will, C L, Sproat, B S, Lührmann, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7664740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00072.x
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