In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

The development of a drug-resistant cell line can take from 3 to 18 months. However, little is published on the methodology of this development process. This article will discuss key decisions to be made prior to starting resistant cell line development; the choice of parent cell line, dose of selec...

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Detalhes bibliográficos
Main Authors: McDermott, Martina, Eustace, Alex J., Busschots, Steven, Breen, Laura, Crown, John, Clynes, Martin, O’Donovan, Norma, Stordal, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944788/
https://ncbi.nlm.nih.gov/pubmed/24639951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00040
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