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Vitamin B6 in Primary Hyperoxaluria I: First Prospective Trial after 40 Years of Practice

BACKGROUND AND OBJECTIVES: Primary hyperoxaluria type I (PH I) is caused by deficiency of the liver-specific enzyme alanine-glyoxylate:aminotransferase (AGT). Many mutations are known to perturb AGT protein folding. Vitamin B6 (B6) is the only specific drug available for treatment. Although B6 has b...

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Detalhes bibliográficos
Main Authors: Hoyer-Kuhn, Heike, Kohbrok, Sina, Volland, Ruth, Franklin, Jeremy, Hero, Barbara, Beck, Bodo B., Hoppe, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944765/
https://ncbi.nlm.nih.gov/pubmed/24385516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.06820613
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