CENP-A Arrays Are More Condensed than Canonical Arrays at Low Ionic Strength

The centromeric histone H3 variant centromeric protein A (CENP-A), whose sequence is the least conserved among all histone variants, is responsible for specifying the location of the centromere. Here, we present a comprehensive study of CENP-A nucleosome arrays by cryo-electron tomography. We see th...

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Detalhes bibliográficos
Main Authors: Geiss, Christian P., Keramisanou, Dimitra, Sekulic, Nikolina, Scheffer, Margot P., Black, Ben E., Frangakis, Achilleas S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944588/
https://ncbi.nlm.nih.gov/pubmed/24559990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.005
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