Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice

Epidemiological studies have suggested an association between pesticide exposure and Parkinson's disease. In this study, we examined the neurotoxicity of an organochlorine pesticide, heptachlor, in vitro and in vivo. In cultured SH-SY5Y cells, heptachlor induced mitochondria-mediated apoptosis....

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Detalhes bibliográficos
Principais autores: Hong, Seokheon, Hwang, Joohyun, Kim, Joo Yeon, Shin, Ki Soon, Kang, Shin Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944446/
https://ncbi.nlm.nih.gov/pubmed/24577234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.12
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