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Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits.

The exocytotic release of potent hormones is a tightly controlled process. Its direct regulation without the involvement of second messengers would ensure rapid signal processing. In streptolysin O-permeabilized insulin-secreting cells, a preparation allowing dialysis of cytosolic macromolecules, ac...

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Dettagli Bibliografici
Autori principali: Lang, J, Nishimoto, I, Okamoto, T, Regazzi, R, Kiraly, C, Weller, U, Wollheim, C B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC394438/
https://ncbi.nlm.nih.gov/pubmed/7641683
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