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The Impact of Unprotected T Cells in RNAi-based Gene Therapy for HIV-AIDS
RNA interference (RNAi) is highly effective in inhibiting human immunodeficiency virus type 1 (HIV-1) replication by the expression of antiviral short hairpin RNA (shRNA) in stably transduced T-cell lines. For the development of a durable gene therapy that prevents viral escape, we proposed to combi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944328/ https://ncbi.nlm.nih.gov/pubmed/24336172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.280 |
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