Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

The antidiabetic drug metformin exerts chemopreventive and antineoplastic effects in many types of malignancies. However, the mechanisms responsible for metformin actions appear diverse and may differ in different types of cancer. Understanding the molecular and cellular mechanisms specific for diff...

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Main Authors: Feng, Y, Ke, C, Tang, Q, Dong, H, Zheng, X, Lin, W, Ke, J, Huang, J, Yeung, S-CJ, Zhang, H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944271/
https://ncbi.nlm.nih.gov/pubmed/24577086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.59
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