Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

The antidiabetic drug metformin exerts chemopreventive and antineoplastic effects in many types of malignancies. However, the mechanisms responsible for metformin actions appear diverse and may differ in different types of cancer. Understanding the molecular and cellular mechanisms specific for diff...

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Bibliographic Details
Main Authors:	Feng, Y, Ke, C, Tang, Q, Dong, H, Zheng, X, Lin, W, Ke, J, Huang, J, Yeung, S-CJ, Zhang, H
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2014
Subjects:	Original Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3944271/ https://ncbi.nlm.nih.gov/pubmed/24577086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.59
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Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

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