DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury

Novel therapeutic targets are required to protect the heart against cell death from acute ischemia–reperfusion injury (IRI). Mutations in the DJ-1 (PARK7) gene in dopaminergic neurons induce mitochondrial dysfunction and a genetic form of Parkinson's disease. Genetic ablation of DJ-1 renders th...

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Detalhes bibliográficos
Main Authors: Dongworth, R K, Mukherjee, U A, Hall, A R, Astin, R, Ong, S-B, Yao, Z, Dyson, A, Szabadkai, G, Davidson, S M, Yellon, D M, Hausenloy, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944257/
https://ncbi.nlm.nih.gov/pubmed/24577080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.41
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