TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer

Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, intrinsic or acquired drug resistance to cisplatin is very common, and leading to...

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Main Authors: Xu, W, Wang, S, Chen, Q, Zhang, Y, Ni, P, Wu, X, Zhang, J, Qiang, F, Li, A, Røe, O D, Xu, S, Wang, M, Zhang, R, Zhou, J
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944244/
https://ncbi.nlm.nih.gov/pubmed/24525731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.27
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