TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer

Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, intrinsic or acquired drug resistance to cisplatin is very common, and leading to...

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Detalhes bibliográficos
Main Authors: Xu, W, Wang, S, Chen, Q, Zhang, Y, Ni, P, Wu, X, Zhang, J, Qiang, F, Li, A, Røe, O D, Xu, S, Wang, M, Zhang, R, Zhou, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944244/
https://ncbi.nlm.nih.gov/pubmed/24525731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.27
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