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Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism

Hyperoxia treatment has been known to induce neuronal and glial death in the developing central nervous system. Retinopathy of prematurity (ROP) is a devastating disease in premature infants and a major cause of childhood vision impairment. Studies indicate that, in addition to vascular injury, reti...

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Detalhes bibliográficos
Main Authors: Narayanan, S P, Xu, Z, Putluri, N, Sreekumar, A, Lemtalsi, T, Caldwell, R W, Caldwell, R B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944241/
https://ncbi.nlm.nih.gov/pubmed/24556690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.23
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