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The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion

The loss of mitochondrial integrity as a consequence of apoptogenic complexes formed on the outer membrane constitutes a key step in controlling progression of apoptotic cascades. Here, we show that multiple members of the linker histone (LH) family of proteins modify apoptotic cascades initiated by...

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Detalhes bibliográficos
Main Authors: Garg, M, Ramdas, N, Vijayalakshmi, M, Shivashankar, G V, Sarin, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944238/
https://ncbi.nlm.nih.gov/pubmed/24525734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.20
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