Selective Inhibition of PI3K/Akt/mTOR Signaling Pathway Regulates Autophagy of Macrophage and Vulnerability of Atherosclerotic Plaque

Macrophage infiltration contributes to the instability of atherosclerotic plaques. In the present study, we investigated whether selective inhibition of PI3K/Akt/mTOR signaling pathway can enhance the stability of atherosclerotic plaques by activation of macrophage autophagy. In vitro study, selecti...

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Autori principali: Zhai, Chungang, Cheng, Jing, Mujahid, Haroon, Wang, Hefeng, Kong, Jing, Yin, Yue, Li, Jifu, Zhang, Yun, Ji, Xiaoping, Chen, Wenqiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944201/
https://ncbi.nlm.nih.gov/pubmed/24599185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090563
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