Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice

Clinical stroke induces inflammatory processes leading to cerebral and splenic injury and profound peripheral immunosuppression. IL-10 expression is elevated during major CNS diseases and limits inflammation in the brain. Recent evidence demonstrated that absence of B-cells led to larger infarct vol...

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Bibliographic Details
Main Authors: Bodhankar, Sheetal, Chen, Yingxin, Vandenbark, Arthur A., Murphy, Stephanie J., Offner, Halina
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944055/
https://ncbi.nlm.nih.gov/pubmed/24374817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-013-9474-3
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