Heterologous Expression of the Thiopeptide Antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor Requires Deletion of Ribosomal Genes from the Expression Construct

GE2270 is a thiopeptide antibiotic generated by extensive posttranslational modifications of a ribosomally generated precursor peptide. Thiopeptides are especially active against Gram-positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). In this study the GE2270 biosynthet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Flinspach, Katrin, Kapitzke, Claudia, Tocchetti, Arianna, Sosio, Margherita, Apel, Alexander K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943966/
https://ncbi.nlm.nih.gov/pubmed/24598591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090499
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak