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Aryl-aldehyde formation in fungal polyketides: Discovery and characterization of a distinct biosynthetic mechanism

Aryl-aldehydes are a common feature in fungal polyketides, which are considered to be exclusively generated by the R domain of non-reducing polyketide synthases (NR-PKSs). However, by cloning and heterologous expression of two cryptic NR-PKS and non-ribosomal peptide synthase (NRPS)-like genes from...

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Autores principales: Wang, Meng, Beissner, Mirko, Zhao, Huimin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943900/
https://ncbi.nlm.nih.gov/pubmed/24412543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.12.005
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