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Hexokinase-II positively regulates glucose starvation induced autophagy through TORC1 inhibition
Hexokinase-II (HK-II) catalyzes the first step of glycolysis and also functions as a protective molecule, however, its role in protective autophagy has not been determined. Results showed that inhibition of HK-II diminished, while overexpression of HK-II potentiated, autophagy induced by glucose dep...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943874/ https://ncbi.nlm.nih.gov/pubmed/24462113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.12.019 |
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