Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation.

A central feature of signal transduction downstream of both receptor and oncogenic tyrosine kinases is the Ras-dependent activation of a protein kinase cascade consisting of Raf-1, Mek (MAP kinase kinase) and ERKs (MAP kinases). To study the role of tyrosine kinase activity in the activation of Raf-...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	EMBO J
Prif Awduron:	Marais, R, Light, Y, Paterson, H F, Marshall, C J
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Nature Publishing Group 1995
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7542586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07316.x
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