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Functional characterization of SIM1-associated enhancers
Haploinsufficiency of the single-minded homology 1 (SIM1) gene in humans and mice leads to severe obesity, suggesting that altered expression of SIM1, by way of regulatory elements such as enhancers, could predispose individuals to obesity. Here, we identified transcriptional enhancers that could re...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943516/ https://ncbi.nlm.nih.gov/pubmed/24203700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt559 |
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