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Cloning, purification, crystallization and preliminary X-ray studies of HMO2 from Saccharomyces cerevisiae

The high-mobility group protein (HMO2) of Saccharomyces cerevisiae is a component of the chromatin-remodelling complex INO80, which is involved in double-strand break (DSB) repair. HMO2 can also bind DNA to protect it from exonucleolytic cleavage. Nevertheless, little structural information is avail...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Zhen, Zhang, Shaocheng, Zhang, Hongpeng, Jin, Li, Zhao, Shasha, Yang, Wei, Tang, Jian, Wang, Deqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943102/
https://ncbi.nlm.nih.gov/pubmed/24419618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13031580
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