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Anti-CD25 antibody mediated depletion of effector T cell populations enhances susceptibility of mice to acute, but not chronic, Toxoplasma gondii infection

Natural regulatory T cells constitutively express the IL-2Rα chain (CD25) on their surface. Consequently, administration of anti-CD25 antibodies is a commonly utilized technique to deplete regulatory T cell populations in vivo. However, activated effector T cells may also transiently express CD25, a...

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Detalhes bibliográficos
Principais autores: Couper, Kevin N., Lanthier, Paula A., Perona-Wright, Georgia, Kummer, Lawrence W., Chen, Wangxue, Smiley, Stephen S., Mohrs, Markus, Johnson, Lawrence L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942880/
https://ncbi.nlm.nih.gov/pubmed/19299696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803053
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