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The Use of the Cre/loxP System to Study Oxidative Stress in Tissue-Specific Manganese Superoxide Dismutase Knockout Models

Significance: Respiring mitochondria are a significant site for reactions involving reactive oxygen and nitrogen species that contribute to irreversible cellular, structural, and functional damage leading to multiple pathological conditions. Manganese superoxide dismutase (MnSOD) is a critical compo...

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Detalhes bibliográficos
Main Authors: Marecki, John C., Parajuli, Nirmala, Crow, John P., MacMillan-Crow, Lee Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942694/
https://ncbi.nlm.nih.gov/pubmed/23641945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5293
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