Generation and characterization of a novel kidney-specific manganese superoxide dismutase knockout mouse

Inactivation of manganese superoxide dismutase (MnSOD), a mitochondrial antioxidant, has been associated with renal disorders and often results in detrimental downstream events that are mechanistically not clear. Development of an animal model that exhibits kidney-specific deficiency of MnSOD would...

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Main Authors: Parajuli, Nirmala, Marine, Akira, Simmons, Sloane, Saba, Hamida, Mitchell, Tanecia, Shimizu, Takahiko, Shirasawa, Takuji, MacMillan-Crow, Lee Ann
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118857/
https://ncbi.nlm.nih.gov/pubmed/21571061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.04.024
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