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An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum

P2X receptors are membrane ion channels gated by extracellular ATP1,2 that are found widely in vertebrates, but not previously in microbes. Here we identify a weakly related gene in the genome of the social amoeba Dictyostelium discoideum, and show, with the use of heterologous expression in human e...

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Detalhes bibliográficos
Main Authors: Fountain, Samuel J., Parkinson, Katie, Young, Mark T., Cao, Lishuang, Thompson, Christopher R. L., North, R. Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942652/
https://ncbi.nlm.nih.gov/pubmed/17625565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05926
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