Prefrontal Cortical GABAergic Dysfunction Contributes to Age-Related Working Memory Impairment

Working memory functions supported by the prefrontal cortex decline in normal aging. Disruption of corticolimbic GABAergic inhibitory circuits can impair working memory in young subjects; however, relatively little is known regarding how aging impacts prefrontal cortical GABAergic signaling and whet...

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Main Authors: Bañuelos, Cristina, Beas, B. Sofia, McQuail, Joseph A., Gilbert, Ryan J., Frazier, Charles J., Setlow, Barry, Bizon, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942567/
https://ncbi.nlm.nih.gov/pubmed/24599447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5192-13.2014
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