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The basal transcription machinery as a target for cancer therapy

General transcription is required for the growth and survival of all living cells. However, tumor cells require extraordinary levels of transcription, including the transcription of ribosomal RNA genes by RNA polymerase I (RNPI) and mRNA by RNA polymerase II (RNPII). In fact, cancer cells have mutat...

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Hlavní autoři: Villicaña, Claudia, Cruz, Grisel, Zurita, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942515/
https://ncbi.nlm.nih.gov/pubmed/24576043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-18
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