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The basal transcription machinery as a target for cancer therapy
General transcription is required for the growth and survival of all living cells. However, tumor cells require extraordinary levels of transcription, including the transcription of ribosomal RNA genes by RNA polymerase I (RNPI) and mRNA by RNA polymerase II (RNPII). In fact, cancer cells have mutat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942515/ https://ncbi.nlm.nih.gov/pubmed/24576043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-18 |
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