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E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases
E-cadherin is an essential adhesion protein as well as a tumor suppressor that is silenced in many cancers. Its adhesion-dependent regulation of signaling has not been elucidated. We report that E-cadherin can negatively regulate, in an adhesion-dependent manner, the ligand-dependent activation of d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC394229/ https://ncbi.nlm.nih.gov/pubmed/15057284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600136 |
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