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Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector.

A human metallothionein (MT) gene was inserted into a bovine papillomavirus (BPV) vector. The chimeric vector (pMTII-BPV) transforms rodent fibroblasts to a cadmium-resistant phenotype. The resistance is due to the high level of expression of human MT-II in those cells. The vector is maintained in t...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Karin, M, Cathala, G, Nguyen-Huu, M C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1983
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6306660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.13.4040
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