Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector.
A human metallothionein (MT) gene was inserted into a bovine papillomavirus (BPV) vector. The chimeric vector (pMTII-BPV) transforms rodent fibroblasts to a cadmium-resistant phenotype. The resistance is due to the high level of expression of human MT-II in those cells. The vector is maintained in t...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1983
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6306660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.13.4040 |
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