Loading...

Aphidicolin inhibits the synthesis and joining of short DNA fragments but not the union of 10-kilobase DNA replication intermediates.

DNA replication intermediates in human melanoma cells have been investigated by using the drug aphidicolin, which inhibits DNA polymerase alpha. In untreated cells, Okazaki fragments and 10-kilobase (kb) DNA intermediates are formed. In aphidicolin-treated cells, the replication fork is stopped and...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lönn, U, Lönn, S
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394186/
https://ncbi.nlm.nih.gov/pubmed/6408640
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!