Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer

Epithelial ovarian cancer presents mostly with serous, endometrioid or mucinous histology but is treated as a single disease. The development of histotype-specific therapy has been challenging because of the relative lack of studies attributing disrupted pathways to a distinct histotype differentiat...

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Main Authors: Tanwar, Pradeep S., Mohapatra, Gayatry, Chiang, Sarah, Engler, David A., Zhang, LiHua, Kaneko-Tarui, Tomoko, Ohguchi, Yasuyo, Birrer, Michael J., Teixeira, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941742/
https://ncbi.nlm.nih.gov/pubmed/24170201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt357
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