Dynamic Regulation of cAMP Synthesis through Anchored PKA-Adenylyl Cyclase V/VI Complexes

Spatiotemporal organization of cAMP signaling begins with the tight control of second messenger synthesis. In response to agonist stimulation of G protein-coupled receptors, membrane-associated adenylyl cyclases (ACs) generate cAMP that diffuses throughout the cell. The availability of cAMP activate...

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Autori principali: Bauman, Andrea L., Soughayer, Joseph, Nguyen, Bao T., Willoughby, Debbie, Carnegie, Graeme K., Wong, Wei, Hoshi, Naoto, Langeberg, Lorene K., Cooper, Dermot M.F., Dessauer, Carmen W., Scott, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941446/
https://ncbi.nlm.nih.gov/pubmed/16973443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.07.025
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