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Cytolysis of nucleated cells by complement: cell death displays multi-hit characteristics.

Lysis of nucleated cells by complement was studied to determine whether the lytic process by C5b-9 conforms to a one-hit mechanism as in the case of erythrocytes. Two nucleated cell lines, Molt 4 and U937, derived from human T lymphocytes and histiocytes, respectively, were employed as targets. The...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Koski, C L, Ramm, L E, Hammer, C H, Mayer, M M, Shin, M L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6602341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.12.3816
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