NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice

BACKGROUND: Bone cancer pain (BCP) is one of the most disabling factors in patients suffering from primary bone cancer or bone metastases. Recent studies show several chemokines (for example, CCL2, CXCL10) in the spinal cord are involved in the pathogenesis of BCP. Here we investigated whether and h...

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Autori principali: Xu, Jie, Zhu, Ming-Di, Zhang, Xin, Tian, Hao, Zhang, Jin-Hua, Wu, Xiao-Bo, Gao, Yong-Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941254/
https://ncbi.nlm.nih.gov/pubmed/24580964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-38
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