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Ubiquitin-Dependent Sorting in Endocytosis

When ubiquitin (Ub) is attached to membrane proteins on the plasma membrane, it directs them through a series of sorting steps that culminate in their delivery to the lumen of the lysosome where they undergo complete proteolysis. Ubiquitin is recognized by a series of complexes that operate at a num...

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Autors principals: Piper, Robert C., Dikic, Ivan, Lukacs, Gergely L.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941215/
https://ncbi.nlm.nih.gov/pubmed/24384571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016808
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