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Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process. We developed three-dimensional (3D) organoid assays to identify the most invasive cancer cells in primary br...

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Detalhes bibliográficos
Main Authors: Cheung, Kevin J., Gabrielson, Edward, Werb, Zena, Ewald, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941206/
https://ncbi.nlm.nih.gov/pubmed/24332913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.029
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