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Factors Affecting the Endothelial Retention of Targeted Microbubbles: Influence of Microbubble Shell Design and Cell Surface Projection of the Endothelial Target Molecule

BACKGROUND: In biologic systems, the arrest of circulating cells is mediated by adhesion molecules projecting their active binding domain above the cell surface to enhance bond formation and tether strength. Similarly, molecular spacers are used for ligands on particle-based molecular imaging agents...

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Bibliografiske detaljer
Main Authors: Khanicheh, Elham, Mitterhuber, Martina, Kinslechner, Katharina, Xu, Lifen, Lindner, Jonathan R., Kaufmann, Beat A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941177/
https://ncbi.nlm.nih.gov/pubmed/22266330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.echo.2011.12.016
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