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Host range transforming gene of polyoma virus plays a role in virus assembly.

Polyoma virus host range transforming (hr-t) mutants are blocked in virion assembly. In normal 3T3 cells, a nonpermissive host, these mutants synthesize 30-40% as much viral DNA and 80-100% as much capsid proteins as does wild-type virus and yet produce only 1-2% as much infectious virus. Intermedia...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Garcea, R L, Benjamin, T L
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6304724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.12.3613
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