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Host range transforming gene of polyoma virus plays a role in virus assembly.
Polyoma virus host range transforming (hr-t) mutants are blocked in virion assembly. In normal 3T3 cells, a nonpermissive host, these mutants synthesize 30-40% as much viral DNA and 80-100% as much capsid proteins as does wild-type virus and yet produce only 1-2% as much infectious virus. Intermedia...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1983
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6304724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.12.3613 |
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