The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers.

Several epidemiologic studies indicate that NAT2-related slow N-acetylation increases bladder cancer risk among workers exposed to aromatic amines, presumably because N-acetylation is important for the detoxification of these compounds. Previously, we showed that NAT2 polymorphisms did not influence...

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Autors principals: Rothman, N, Bhatnagar, V K, Hayes, R B, Zenser, T V, Kashyap, S K, Butler, M A, Bell, D A, Lakshmi, V, Jaeger, M, Kashyap, R
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC39410/
https://ncbi.nlm.nih.gov/pubmed/8643532
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