The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers.

Several epidemiologic studies indicate that NAT2-related slow N-acetylation increases bladder cancer risk among workers exposed to aromatic amines, presumably because N-acetylation is important for the detoxification of these compounds. Previously, we showed that NAT2 polymorphisms did not influence...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rothman, N, Bhatnagar, V K, Hayes, R B, Zenser, T V, Kashyap, S K, Butler, M A, Bell, D A, Lakshmi, V, Jaeger, M, Kashyap, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.5084
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