Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements

MeCP2 is a critical epigenetic regulator in brain and its abnormal expression or compromised function leads to a spectrum of neurological disorders including Rett Syndrome and autism. Altered expression of the two MeCP2 isoforms, MeCP2E1 and MeCP2E2 has been implicated in neurological complications....

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Detaylı Bibliyografya
Asıl Yazarlar: Olson, Carl O., Zachariah, Robby M., Ezeonwuka, Chinelo D., Liyanage, Vichithra R. B., Rastegar, Mojgan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940938/
https://ncbi.nlm.nih.gov/pubmed/24594659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090645
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